Netcare 911 paramedics and other services responded to an accident on the N2 north bound approximately two kilometres before the Ballito off-ramp in KZN.
Upon their arrival on scene they found that two vehicles collided. One vehicle burst into flames and the second vehicle came to a standstill down an embankment.
The Kwa Dakuza Fire and Rescue team extinguished the burning vehicle.
One person was found to be in a critical condition and after receiving treatment on scene, the patient rushed to hospital for urgent medical care.
A further five people sustained minor to moderate injuries.
Exact detail to the cause of the accident and preceding events will remain the subject of a police investigation.